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The results from the STRIVE trial of Enzalutamide ( Xtandi ) compared to Bicalutamide ( Casodex ) in men with castration-resistant prostate cancer ( CRPC ) are published in the Journal of Clinical Onc ...


The results from the phase 2 TERRAIN trial of Enzalutamide ( Xtandi ) compared to Bicalutamide ( Casodex ) in metastatic castration-resistant prostate cancer ( CRPC ) are published in the Lancet Oncol ...


Recent guidelines recommend against routine screening for prostate cancer, partly because of the risks associated with overtreatment of clinically indolent tumours. A study aimed to determine the ...


A study has analyzed the proportion of men taking Tadalafil ( Cialis ) 5 mg once-daily who reach a combined improvement ( henceforth known as a combined responder ) in symptoms of both erectile dysfun ...


Treatment with Cabozantinib ( Cometriq ) has reduced the rate of disease progression or death by 42% compared to Everolimus ( Afinitor ) in METEOR, a phase III trial comparing Cabozantinib to Everolim ...


It has been shown that increased prostate size is a risk factor for lower urinary tract symptom ( LUTS ) progression in men who currently have LUTS presumed due to benign prostatic hyperplasia ( BPH ) ...


Transurethral resection of the prostate ( TURP ) is considered gold standard for surgical treatment of benign prostatic hyperplasia ( BPH ). In this study, researchers aimed to compare post-operativ ...


A study has investigated the clinical and urodynamic features of patients with lower urinary tract symptoms/benign prostatic hyperplasia ( LUTS/BPH ) according to their prostate size. Researchers a ...


Patients with lower urinary tract symptoms ( LUTS ) have a higher prevalence of cardiovascular disease. Researchers have evaluated the correlation between LUTS and cardiovascular risk factors in men p ...


A study has compared postoperative pain scores and assessed efficacy between an adjustable single-incision sling and a standard transobturator sling for stress urinary incontinence ( SUI ). The sin ...


In the IMvigor 210 study, the investigational cancer immunotherapy Atezolizumab ( MPDL3280A; anti-PD-L1 ) shrank tumors ( objective response rate; ORR; the primary end point of this study ) in people ...


Penile fracture is an uncommon urologic emergency, defined as traumatic rupture of the tunica albuginea of the corpus cavernosum. It occurs mainly in young adults during sexual activity. In the Un ...


The identification of biomarkers in urine or serum samples from patients with bladder cancer is urgently required for the development of non-invasive methods for the diagnosis of bladder carcinoma and ...


A study has examined the safety of intralesional injection of Collagenase Clostridium histolyticum ( CCH; Xiapex ) for the treatment of Peyronie's disease, using a pooled safety analysis of subjects ...


In a phase III clinical trial, the hormone therapy Enzalutamide ( Xtandi ) extended survival in men with metastatic prostate cancer that had progressed during treatment with androgen deprivation thera ...


Results from a phase I open-label study that showed the investigational cancer immunotherapy MPDL3280A ( anti-PDL1 ) shrank tumours ( overall response rate ) in 43% ( 13/30 ) of people previously trea ...


Results from the phase III study of Triptorelin pamoate 11.25 mg ( Decapeptyl 3 months ) administered subcutaneously in patients with locally advanced or metastatic prostate cancer were presented at t ...


The androgen receptor inhibitor, Enzalutamide ( Xtandi ) is approved for the treatment of metastatic castration-resistant prostate cancer that has progressed on Docetaxel. A study has assessed the ac ...


Tadalafil ( Cialis ) is used to treat erectile dysfunction after prostate cancer treatment, but its role as a preventive agent is undefined. A study has assessed primarily whether Tadalafil preserv ...


Radical prostatectomy reduces mortality among men with localized prostate cancer; however, important questions regarding long-term benefit remain. Between 1989 and 1999, researchers have randomly a ...


Ipsen has announced positive results from its phase IIa clinical trial assessing Dysport in the treatment of neurogenic detrusor overactivity ( NDO ) in patients with urinary incontinence not adequate ...


Surgery is a craft profession requiring individuals with specific, well-documented innate aptitude for manipulative skills. Yet in most countries, the current selection process of surgical trainees do ...


The potential rehabilitative and protective effect of phosphodiesterase type 5 inhibitors ( PDE5-Is ) on penile function after nerve-sparing radical prostatectomy ( NSRP ) remains unclear. The prim ...


A second large, prospective study by researchers at Fred Hutchinson Cancer Research Center ( Seattle; United States ) has confirmed the link between high blood concentrations of Omega-3 fatty acids an ...


Overdiagnosis and subsequent overtreatment are important side effects of screening for, and early detection of, prostate cancer ( PCa ). Active surveillance ( AS ) is of growing interest as an alterna ...


Data from the pivotal Phase III ALSYMPCA ( ALpharadin in SYMptomatic Prostate CAncer ) trial of its drug Radium 223 dichloride ( Radium 223 ) in castration-resistant prostate cancer patients with symp ...


A study, published in the Journal of Clinical Sleep Medicine, suggests that the bladder condition nocturia may worsen the already poor sleep of older adults with insomnia.The research has involved a g ...


Prostate cancer aggressiveness may be established when the tumor is formed and not alter with time, according to a study published in Cancer Research, a journal of the American Association for Cancer ...


Researchers has assessed effectiveness, safety, and tolerability of Paclitaxel or Fluorouracil when added to radiation plus Cisplatin followed by adjuvant chemotherapy in a programme of selected bladd ...


The FDA ( Food and Drug Administration ) has approved a product label addition for Cialis ( Tadalafil ) to include data from a 26-week study that showed Cialis 5 mg for once daily use started in combi ...


Replacing carbohydrates and animal fat with vegetable fat may be associated with a lower risk of death in men with nonmetastatic prostate cancer. Nearly 2.5 million men currently live with prostate ...


Avanafil ( Stendra, Spedra, Zepeeed ) is an oral phosphodiesterase type 5 inhibitor indicated for the treatment of erectile dysfunction. Avanafil is rapidly absorbed after oral administration, with ...


New research from the School of Medicine at The University of Texas Health Science Center San Antonio has indicated that eating a modest amount of walnuts can protect against prostate cancer. The s ...


In a study that included more than 10,000 men with nonmetastatic prostate cancer, use of androgen deprivation therapy ( ADT ) was associated with a significantly increased risk of acute kidney injury, ...


A new study from Harvard School of Public Health ( HSPH ) and Brigham and Women's Hospital researchers has found a strong association between the common sexually transmitted infection, Trichomonas vag ...


Two medications used to treat erectile dysfunction in men [ Tadalafil ( Cialis ) and Sildenafil ( Viagra ) ] do not appear to have visual side effects when taken daily for six months, despite concerns ...


About one half of all bladder neoplasms are non-invasive, and in those, the histologic grade is a crucial prognosticator. Few single-Center studies have assessed the recurrence, progression, and can ...


Around 16% to 45% of adults have overactive bladder symptoms, urgency with frequency or urgency urinary incontinence, or both, termed overactive bladder syndrome. Anticholinergic drugs are common trea ...


An analysis has compared long-term urinary, bowel, and sexual function after radical prostatectomy or external-beam radiation therapy.The Prostate Cancer Outcomes Study ( PCOS ) enrolled 3533 men in w ...


Typically in invasive papillary urothelial carcinoma both the overlying papillary and the invasive components are high grade. Researches have described a series of patients with invasive low-grade ...


A comparison of outcomes of different eras of conservative treatment for localized prostate cancer indicates that overall and prostate cancer-specific survival rates are higher for men diagnosed from ...


Hormone therapy used to treat men with advanced prostate cancer is associated with an increased chance of developing various heart problems. Some choices of therapy appear, however, to be less risky t ...


It is argued that a rapidly rising PSA may indicate a greater risk of diagnosis of prostate cancer even if PSA levels are low. Some guidelines do incorporate PSA velocity cut points as an indication f ...


Patients with early bladder cancer who receive more intensive treatment within the first two years of diagnosis do not appear to have better survival than patients who receive less intensive treatment ...


The carcinogen Aristolochic acid, which was found in many prescribed Chinese herbal products including Guan Mu Tong, is associated with an increased risk of urinary tract cancer.Many countries, such a ...


Adding chemotherapy to radiation therapy for muscle invasive bladder cancer allows 67% of people to be free of disease in their bladders two years after treatment. This compares to 54% of people who r ...


Men aged 55 to 74 years who have low baseline blood levels of prostate specific antigen ( PSA ) are not likely to benefit from further screening and treatment. That is the conclusion of a new study pu ...


A study from Harvard School of Public Health and Brigham and Women's Hospital researchers has found a strong association between the common sexually transmitted infection, Trichomonas vaginalis, and r ...


Men with lower cholesterol are less likely than those with higher levels to develop high-grade prostate cancer. In a prospective study of more than 5,000 US men, epidemiologists say they now have evi ...


Benign prostatic hyperplasia ( BPH ) is a common condition in aging men. It has been estimated that more than 8 million United States men age 50 to 79 years will meet current guidelines for consider ...



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