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For men with intermediate risk prostate cancer, radiation treatment with brachytherapy alone can result in similar cancer control with fewer long-term side effects, when compared to more aggressive tr ...


While some previous studies have indicated that taking erectile dysfunction ( ED ) drugs may reduce the likelihood of developing prostate cancer, new research found that these drugs do not play a role ...


Nitrate is a drinking water contaminant arising from agricultural sources and a precursor in the endogenous formation of N-nitroso compounds ( NOC ), which are possible bladder carcinogens. A study ...


Intestinal metaplasia of the bladder is an uncommon glandular proliferation. Researchers have examined a large series of intestinal metaplasia for the clinicopathological features and discuss the sign ...


Body mass index ( BMI ) has been associated with worse outcomes in several solid malignancies. A study has evaluated the association between BMI and oncological outcomes in patients treated with radic ...


Preclinical urothelial carcinoma models suggest activity of Dasatinib ( Sprycel ), an oral Src-family kinase ( SFK ) inhibitor. Researchers have determined the feasibility and biologic activity of n ...


Researchers have evaluated the association of ABO blood type with clinicopathologic outcomes and mortality among patients with urothelial carcinoma of the bladder treated with radical cystectomy. 2 ...


Late recurrence of renal cell carcinoma is not a rare event. A retrospective study has investigated the clinicopathological features and the outcome of patients treated with Sorafenib ( Nexavar ), Sun ...


Researchers aimed to identify clinical predictors of long-term response to Abiraterone [ Zytiga ] ( defined as more than 12 months drug exposure ) in a retrospective cohort of metastatic castration-re ...


Pancreatic metastases from renal cell carcinoma are uncommon and their prognostic significance is not well defined. Br> An analysis has evaluated the outcome of patients with pancreatic metastas ...


Studies investigating the association of food and nutrient consumption with the risk of urothelial cell carcinoma ( UCC ) have produced mixed results. Researchers used three common dietary scores, t ...


Little is known about the outcomes and prognostic factors of adjuvant chemotherapy for locally advanced penile squamous cell carcinoma after regional lymphadenectomy ( LAD ). Researchers have retro ...


The efficacy and safety of a combination of chemotherapeutic agent compared with single-agent chemotherapy in the second-line setting of advanced urothelial carcinoma ( UC ) are unclear. Researchers ...


The FDA ( U.S. Food and Drug Administration ) has granted accelerated approval to Tecentriq ( Atezolizumab ) for the treatment of people with locally advanced or metastatic urothelial carcinoma ( mUC ...


Ureteral stent-related pain is a well-known side effect of stent placement. To date, there is a paucity of resources that address this topic. Stent pain pathophysiology is multifactorial and likely ...


The results from the STRIVE trial of Enzalutamide ( Xtandi ) compared to Bicalutamide ( Casodex ) in men with castration-resistant prostate cancer ( CRPC ) are published in the Journal of Clinical Onc ...


The results from the phase 2 TERRAIN trial of Enzalutamide ( Xtandi ) compared to Bicalutamide ( Casodex ) in metastatic castration-resistant prostate cancer ( CRPC ) are published in the Lancet Oncol ...


Recent guidelines recommend against routine screening for prostate cancer, partly because of the risks associated with overtreatment of clinically indolent tumours. A study aimed to determine the ...


A study has analyzed the proportion of men taking Tadalafil ( Cialis ) 5 mg once-daily who reach a combined improvement ( henceforth known as a combined responder ) in symptoms of both erectile dysfun ...


Patients with metastatic renal cell carcinoma ( mRCC ) received Sunitinib ( Sutent ) in a global expanded-access program ( EAP ). Efficacy and safety results for the EAP subpopulation in Italy were r ...


Treatment with Cabozantinib ( Cometriq ) has reduced the rate of disease progression or death by 42% compared to Everolimus ( Afinitor ) in METEOR, a phase III trial comparing Cabozantinib to Everolim ...


It has been shown that increased prostate size is a risk factor for lower urinary tract symptom ( LUTS ) progression in men who currently have LUTS presumed due to benign prostatic hyperplasia ( BPH ) ...


Transurethral resection of the prostate ( TURP ) is considered gold standard for surgical treatment of benign prostatic hyperplasia ( BPH ). In this study, researchers aimed to compare post-operativ ...


A study has investigated the clinical and urodynamic features of patients with lower urinary tract symptoms/benign prostatic hyperplasia ( LUTS/BPH ) according to their prostate size. Researchers a ...


Patients with lower urinary tract symptoms ( LUTS ) have a higher prevalence of cardiovascular disease. Researchers have evaluated the correlation between LUTS and cardiovascular risk factors in men p ...


A study has compared postoperative pain scores and assessed efficacy between an adjustable single-incision sling and a standard transobturator sling for stress urinary incontinence ( SUI ). The sin ...


In the IMvigor 210 study, the investigational cancer immunotherapy Atezolizumab ( MPDL3280A; anti-PD-L1 ) shrank tumors ( objective response rate; ORR; the primary end point of this study ) in people ...


Penile fracture is an uncommon urologic emergency, defined as traumatic rupture of the tunica albuginea of the corpus cavernosum. It occurs mainly in young adults during sexual activity. In the Un ...


The identification of biomarkers in urine or serum samples from patients with bladder cancer is urgently required for the development of non-invasive methods for the diagnosis of bladder carcinoma and ...


A study has examined the safety of intralesional injection of Collagenase Clostridium histolyticum ( CCH; Xiapex ) for the treatment of Peyronie's disease, using a pooled safety analysis of subjects ...


In a phase III clinical trial, the hormone therapy Enzalutamide ( Xtandi ) extended survival in men with metastatic prostate cancer that had progressed during treatment with androgen deprivation thera ...


Results from a phase I open-label study that showed the investigational cancer immunotherapy MPDL3280A ( anti-PDL1 ) shrank tumours ( overall response rate ) in 43% ( 13/30 ) of people previously trea ...


Results from the phase III study of Triptorelin pamoate 11.25 mg ( Decapeptyl 3 months ) administered subcutaneously in patients with locally advanced or metastatic prostate cancer were presented at t ...


The androgen receptor inhibitor, Enzalutamide ( Xtandi ) is approved for the treatment of metastatic castration-resistant prostate cancer that has progressed on Docetaxel. A study has assessed the ac ...


Tadalafil ( Cialis ) is used to treat erectile dysfunction after prostate cancer treatment, but its role as a preventive agent is undefined. A study has assessed primarily whether Tadalafil preserv ...


Radical prostatectomy reduces mortality among men with localized prostate cancer; however, important questions regarding long-term benefit remain. Between 1989 and 1999, researchers have randomly a ...


Ipsen has announced positive results from its phase IIa clinical trial assessing Dysport in the treatment of neurogenic detrusor overactivity ( NDO ) in patients with urinary incontinence not adequate ...


Surgery is a craft profession requiring individuals with specific, well-documented innate aptitude for manipulative skills. Yet in most countries, the current selection process of surgical trainees do ...


The potential rehabilitative and protective effect of phosphodiesterase type 5 inhibitors ( PDE5-Is ) on penile function after nerve-sparing radical prostatectomy ( NSRP ) remains unclear. The prim ...


A second large, prospective study by researchers at Fred Hutchinson Cancer Research Center ( Seattle; United States ) has confirmed the link between high blood concentrations of Omega-3 fatty acids an ...


Overdiagnosis and subsequent overtreatment are important side effects of screening for, and early detection of, prostate cancer ( PCa ). Active surveillance ( AS ) is of growing interest as an alterna ...


Data from the pivotal Phase III ALSYMPCA ( ALpharadin in SYMptomatic Prostate CAncer ) trial of its drug Radium 223 dichloride ( Radium 223 ) in castration-resistant prostate cancer patients with symp ...


A study, published in the Journal of Clinical Sleep Medicine, suggests that the bladder condition nocturia may worsen the already poor sleep of older adults with insomnia.The research has involved a g ...


Prostate cancer aggressiveness may be established when the tumor is formed and not alter with time, according to a study published in Cancer Research, a journal of the American Association for Cancer ...


Researchers has assessed effectiveness, safety, and tolerability of Paclitaxel or Fluorouracil when added to radiation plus Cisplatin followed by adjuvant chemotherapy in a programme of selected bladd ...


The FDA ( Food and Drug Administration ) has approved a product label addition for Cialis ( Tadalafil ) to include data from a 26-week study that showed Cialis 5 mg for once daily use started in combi ...


Replacing carbohydrates and animal fat with vegetable fat may be associated with a lower risk of death in men with nonmetastatic prostate cancer. Nearly 2.5 million men currently live with prostate ...


Avanafil ( Stendra, Spedra, Zepeeed ) is an oral phosphodiesterase type 5 inhibitor indicated for the treatment of erectile dysfunction. Avanafil is rapidly absorbed after oral administration, with ...


New research from the School of Medicine at The University of Texas Health Science Center San Antonio has indicated that eating a modest amount of walnuts can protect against prostate cancer. The s ...


In a study that included more than 10,000 men with nonmetastatic prostate cancer, use of androgen deprivation therapy ( ADT ) was associated with a significantly increased risk of acute kidney injury, ...